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Global disease hotspots

Ian Williamson takes a look at whch regions in the world to avoid if
you don’t want to catch some pretty nasty diseases.


The world is shrinking as global travel becomes the norm. Expatriates, too, do not just stick to the tried and tested destinations of the past. Some will live and work in what in a previous age might have been called ‘exotic locations’ – which means you don’t have to go far to be at potential risk from a travel-related illness. However, with sensible planning and behaviour, the world soon becomes a safer place to visit.

Estimates suggest that 80 per cent of travellers to developing countries suffer diarrhoea or feel unwell due to their journey. For significant illnesses, such as HIV, typhoid, cholera and meningococcal disease, the figure falls to less than 0.1 per cent of 100,000 travellers per month. So, clearly, precautions should be tailored to the risk. Watch out for drinking the local water, if you want to avoid the former unpleasantness. For the latter, more serious threats, there are a few things to bear in mind.

Last year a man died from rabies in the UK after contracting the disease while visiting his family in the Philippines. Despite being given the rabies vaccine to boost his immune system’s response to the virus within an hour of being admitted to hospital, he succumbed to the disease.

The last case of rabies in the UK was in the 1960s. Although scientists in the USA claimed late last year that new drugs had been effective in treating full-blown rabies, they are not commonly available and once rabies symptoms appear, there is no cure for the disease. Rabies attacks the central nervous system, and acts a little like a neuro-toxin.

The only way to act once you have been bitten by an animal you suspect might be infected is to get to hospital immediately. A series of vaccinations can prevent the disease getting hold of your nervous system. But once it has appeared in full-blown form, there is little hope for cure. Apart from a few islands – Hawaii and the UK are notable – rabies is common throughout the world. So, be very aware of the risk.

One of the problems with trying to pin down disease hot spots at any one time is that outbreaks of a disease move across the globe in an ever-changing pattern.

Take the case of anthrax in Zimbabwe. A year ago, no one would have associated Zimbabwe with this disease but with the unrest following the farm takeovers by war veterans, herds of different breeds of cattle have been mixed together. Veterinary inspectors have been denied access to the new mixed herds. As a result, there has been an outbreak of anthrax in the country.

Travellers could be at risk if they eat infected animals – although anthrax has other mechanisms of transmission such as through inhalation and, in some cases, through the skin. Anthrax spores can remain active in the soil for years. Anyone visiting other anthrax regions – such as Asia, the Middle East, Iran, Russia and parts of Africa – should avoid contact with raw animal products including meats, carcasses and hides. Treatment for Anthrax is much like that for rabies: prior to the onset of symptoms, antibiotics are generally effective. But once the disease has taken hold, the prognosis is poor.

Another re-emerging infection is dengue fever, a viral disease transmitted by mosquitoes. With increasing travel through tropical and semi-tropical regions, this disease is now second only to malaria as the most prevalent insect-borne disease in the tropics – even including areas where it was once thought to have been eradicated.

There is currently no vaccine available against dengue fever, so it is best to take precautions to avoid being bitten by mosquitoes in the first place. Prevention of mosquito bites should be the prime consideration for any traveller in less-well-developed regions.

Yellow fever, another mosquito-borne virus, remains on the list of major world health concerns for travellers as one infected person can introduce it to a new area and trigger an epidemic. The mosquito is found mainly in tropical South America and Africa from the Sahara desert southwards, down through Nigeria, Angola and Kenya. International law now requires those leaving infected areas to show proof of vaccination before being allowed entry into countries concerned about the yellow fever risk. Like dengue fever, preventing bites by mosquitoes is crucial.

HIV infection remains a constant threat and nowhere more so than in central Africa. Up to one in seven of the population are HIV-positive and the vast majority through heterosexual intercourse. In Thailand and India there is up to an 80 per cent infection rate among prostitutes, making unprotected sex a greater danger than Russian roulette. Clearly, unprotected sex is a big no-no in such regions.

Northern Europe is not immune to its own disease hotspots but the incidence of communicable diseases in most areas are unlikely to provide a health hazard to the international traveller greater than that found in his home country. However, the incidence of certain food-borne diseases such as salmonella and campylobacter, is significantly increasing in some countries. And rabies remains endemic in wild animals (especially foxes) in rural areas of northern Europe.

In other parts of the world, where rabies is a significant risk, there may be a shortage of the rabies vaccine and immunoglobulin, so always obtain a series of three anti-rabies injections before you travel; this greatly simplifies any post-bite rabies treatment you may need.

When it comes to international travel, especially to less developed parts of the world, a little prior knowledge can prove invaluable and sometimes be a lifesaver.

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